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  • 产品名称:anti-SERPINB9antibody(serpinPeptidaseInhibitor,CladeB(Ovalbumin),Member9)(AA122

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简单介绍:
anti-SERPINB9antibody(serpinPeptidaseInhibitor,CladeB(Ovalbumin),Member9)(AA122-150)
详情介绍:
Immunogen This SERPINB9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-150 amino acids from the Central region of human SERPINB9.
Clone RB41820
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name SERPINB9 (SERPINB9 Antibody Abstract)
Background PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis .

Synonyms: SERPINB9, PI9, Serpin B9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9
NCBI Accession NP_004146
UniProt P50453
Research Area Proteases
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 9 (SERPINB9) (AA 122-150), (Center) antibody (ABIN1881792) SERPINB9 Antibody (Center) (ABIN1881792) western blot analysis in NCI-H292 cell line ...
Background publications Rousalova, Krepela, Prochazka, Cermak, Benkova: "Expression of proteinase inhibitor-9/serpinB9 in non-small cell lung carcinoma cells and tissues." in: International journal of oncology, Vol. 36, Issue 1, pp. 275-83, 2009 (PubMed).

Jiang, Patterson, Ling, Xie, Helferich, Shapiro: "Low concentrations of the soy phytoestrogen genistein induce proteinase inhibitor 9 and block killing of breast cancer cells by immune cells." in: Endocrinology, Vol. 149, Issue 11, pp. 5366-73, 2008 (PubMed).

Bots, de Bruin, Rademaker-Koot, Medema: "Proteinase inhibitor-9 expression is induced by maturation in dendritic cells via p38 MAP kinase." in: Human immunology, Vol. 68, Issue 12, pp. 959-64, 2008 (PubMed).

Kummer, Micheau, Schneider, Bovenschen, Broekhuizen, Quadir, Strik, Hack, Tschopp: "Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis." in: Cell death and differentiation, Vol. 14, Issue 8, pp. 1486-96, 2007 (PubMed).

Jiang, Ellison, Alarid, Shapiro: "Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells." in: Oncogene, Vol. 26, Issue 28, pp. 4106-14, 2007 (PubMed).

Sprecher, Morgenstern, Mathewes, Dahlen, Schrader, Foster, Kisiel: "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors." in: The Journal of biological chemistry, Vol. 270, Issue 50, pp. 29854-61, 1996 (PubMed).