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  • 产品名称:anti-Keratin72(KRT72)(AA313-342),(Center)antibody

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简单介绍:
anti-Keratin72(KRT72)(AA313-342),(Center)antibody
详情介绍:
Immunogen This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.
Clone RB40960
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name KRT72 (KRT72 Antibody Abstract)
Background Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: KRT72, K6IRS2, KB35, KRT6, KRT6IRS2, Keratin, type II cytoskeletal 72, Cytokeratin-72, Keratin-72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35
NCBI Accession NP_001139698, NP_001139697, NP_542785
UniProt Q14CN4
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Keratin 72 (KRT72) (AA 313-342), (Center) antibody (ABIN1881487) KRT72 Antibody (Center) (ABIN1881487) western blot analysis in human Uterus tissue ly...
Product cited in: Langbein, Rogers, Praetzel, Winter, Schweizer: "K6irs1, K6irs2, K6irs3, and K6irs4 represent the inner-root-sheath-specific type II epithelial keratins of the human hair follicle." in: The Journal of investigative dermatology, Vol. 120, Issue 4, pp. 512-22, 2003 (PubMed).

Porter, Corden, Lunny, Smith, Lane, McLean: "Keratin K6irs is specific to the inner root sheath of hair follicles in mice and humans." in: The British journal of dermatology, Vol. 145, Issue 4, pp. 558-68, 2001 (PubMed).