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  • 产品名称:anti-Gem(NuclearOrganelle)AssociatedProtein2(GEMIN2)antibody

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简单介绍:
anti-Gem(NuclearOrganelle)AssociatedProtein2(GEMIN2)antibody
详情介绍:
Immunogen Synthetic peptide of human GEMIN2
Isotype IgG
Purification Antigen affinity purification
Alternative Name GEMIN2 (GEMIN2 Antibody Abstract)
Background This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Synonyms: SIP1, SIP1-delta
Pathways Ribonucleoprotein Complex Subunit Organization, Tube Formation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) antibody (ABIN2431833) Immunohistochemistry of Human ovarian cancer using GEMIN2 Polyclonal Antibody at dilu...