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  • 产品名称:anti-CD25antibody(Interleukin2Receptor,alpha)

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简单介绍:
anti-CD25antibody(Interleukin2Receptor,alpha)
详情介绍:
Immunogen Synthetic peptide of human IL2RA
Isotype IgG
Purification Antigen affinity purification
Alternative Name IL2RA (IL2RA Antibody Abstract)
Background The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency
Synonyms: CD25, IL2R, TCGFR, IDDM10
Pathways JAK-STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Interleukin 2 Receptor, alpha (IL2RA) antibody (ABIN2431535) Immunohistochemistry of Human liver cancer using IL2RA Polyclonal Antibody at dilutio...