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  • 产品名称：anti-SynaptotagminIII(SYT3)antibody

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简单介绍：
anti-SynaptotagminIII(SYT3)antibody
详情介绍：
Immunogen Recombinant protein of human SYT3
Isotype IgG
Purification Antigen affinity purification
Alternative Name SYT3 (SYT3 Antibody Abstract)
Background Synaptotagmins are a large gene family of synaptic vesicle type III integral membrane proteins that function as regulators of both exocytosis and endocytosis and are involved in neurotransmitter secretion from small secretory vesicles. Calcium binds to Synaptotagmin I which triggers neurotransmitter release at the synapse. Synaptotagmin II is phosphorylated by WNK1 in a process that regulates calcium-dependent interactions. Synaptotagmin III is involved in calcium-dependent exocytosis of secretory vesicles in endocrine cells and neurons. Synaptotagmin IV is expressed in neuronal tissues, and has the highest mRNA levels in the hippocampus. The proximity of the Synaptotagmin IV gene to markers of several psychiatric disorders suggest an involvement of synaptotagmin IV in human disease. Synaptotagmin V is a dense-core vesicle-specific protein that regulates a specific type of calcium-regulated secretion. Synaptotagmin VI interacts with adaptor protein-2 in a calcium-independent manner. Synaptotagmin VII is widely expressed in non-neuronal tissues.
Synonyms: SytIII
Pathways Synaptic Vesicle Exocytosis
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Synaptotagmin III (SYT3) antibody (ABIN2428761) Immunohistochemistry of Human brain using SYT3 Polyclonal Antibody at dilution of 1:50