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  • 产品名称：anti-EPORantibody(ErythropoietinReceptor)

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简单介绍：
anti-EPORantibody(ErythropoietinReceptor)
详情介绍：
Immunogen Synthetic peptide of human EPOR
Isotype IgG
Purification Antigen affinity purification
Alternative Name EPOR (EPOR Antibody Abstract)
Background This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Synonyms: EPO-R
Pathways JAK-STAT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Erythropoietin Receptor (EPOR) antibody (ABIN2431305) Immunohistochemistry of Human brain using EPOR Polyclonal Antibody at dilution of 1:40