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  • 产品名称:anti-LIG1antibody(LigaseI,DNA,ATP-Dependent)

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简单介绍:
anti-LIG1antibody(LigaseI,DNA,ATP-Dependent)
详情介绍:
Immunogen Recombinant protein of human LIG1
Isotype IgG
Purification Antigen affinity purification
Alternative Name LIG1 (LIG1 Antibody Abstract)
Background This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
Pathways Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-Ligase I, DNA, ATP-Dependent (LIG1) antibody (ABIN2429953) Immunohistochemistry of Human breast cancer using LIG1 Polyclonal Antibody at dilutio...