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  • 产品名称:anti-PHLPP1antibody(PHDomainandLeucineRichRepeatProteinPhosphatase1)

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简单介绍:
anti-PHLPP1antibody(PHDomainandLeucineRichRepeatProteinPhosphatase1)
详情介绍:
Immunogen Recombinant protein of human PHLPP1
Isotype IgG
Purification Antigen affinity purification
Alternative Name PHLPP1 (PHLPP1 Antibody Abstract)
Background This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.
Synonyms: PHLPP1
Pathways PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Handling Advice Avoid freeze / thaw cycles.
Storage -20 °C/-80 °C
Storage Comment Store at -20°C (regular) and -80°C (long term).
Supplier Images
Immunohistochemistry (IHC) image for anti-PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1) antibody (ABIN2430635) Immunohistochemistry of Human liver cancer using PHLPP1 Polyclonal Antibody at diluti...