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  • 产品名称:Leflunomide

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简单介绍:
Leflunomide
详情介绍:
Purpose Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Characteristics Tradename: ARAVA
Source of Compound: synthetic, SU-101, HWA-486
Target: Protein-tyrosine kinase 2 antagonist,AhR agonist,Dehydrogenase inhibitor
Receptor: Protein-tyrosine kinase 2,AhR,DHODH
Status: USAN, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 99 %
Formula C12H9F3N2O2
Solubility Soluble in DMSO
Molecular Weight 270.21 g/mol
CAS-No 75706-12-6
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months