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  • 产品名称：Thalidomide

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  • 产品厂商：TargetMol
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简单介绍：
Thalidomide
详情介绍：
Purpose A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
Characteristics Tradename: THALOMID
Source of Compound: synthetic, K-17
Target: NF-κB inhibitor,TNF inhibitor,COX,FGFR inhibitor
Receptor: NF-κB,TNF,Protein cereblon,α1-acid glycoprotein,Prostaglandin G/H synthase 2,FGFR2
Status: USP, INN, BAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Purity 98 %
Formula C13H10N2O4
Solubility 10 mM in DMSO
Molecular Weight 258.23 g/mol
CAS-No 50-35-1
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Storage -20 °C
Storage Comment For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Expiry Date 24 months
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