anti-NeurofilamentL(AA1-284)antibody 抗体网

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产品名称：anti-NeurofilamentL(AA1-284)antibody
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产品厂商：SYSY
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简单介绍：

anti-NeurofilamentL(AA1-284)antibody

详情介绍：

Product details
Product details
Immunogen	Recombinant Strep-Tag? fusion protein of human neurofilament L (aa 1-284).
Specificity	Specific for neurofilament L.
Purification	antiserum

Target details
Target details
Background	Synonyms: NF-L, NF 68

Application Details
Application Details
Application Notes	WB: 1 : 1000 (AP staining) ICC: 1 : 500 IHC: 1 : 200
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Buffer	PBS
Handling Advice	Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4?°C. Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20?°C),however, is preferable.
Storage	4 °C/-20 °C
Storage Comment	Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

Images
Images
Supplier Images	dilution: 1 : 1000, sample: rat brain homogenate Indirect immunohystochemistry of a rat gyrus dentatus section (dilution 1 : 200). Indirect immunostaining of PFA fixed rat hippocampus neurons with anti-Neurofilament ... Immunostaining of PFA fixed, paraffin embedded section of a 5 x FAD mouse mouse brain... Images for product: anti-Neurofilament L (AA 1-284) antibody dilution: 1 : 1000, sample: rat brain homogenate Indirect immunohystochemistry of a rat gyrus dentatus section (dilution 1 : 200). Indirect immunostaining of PFA fixed rat hippocampus neurons with anti-Neurofilament L (dilution 1 : 500; red) and mouse anti-Synapsin 1 (cat. no. 106 011, dilution 1 : 1000; green). Nuclei have been visualized by DAPI staining (blue). Immunostaining of PFA fixed, paraffin embedded section of a 5 x FAD mouse mouse brain. Immunoreactivity was revealed using diaminobenzidine as chromagen. Nuclei were counterstained with haematoxylin (blue). Increase numbers of axonal swellings become apparent in this Alzheimer mouse model.

References
References
Product cited in:	Richard, Kurdakova, Baches, Bayer, Weggen, Wirths: "Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 45, Issue 4, pp. 1223-36, 2015 (PubMed). Pérez-García, Burden: "Increasing MuSK activity delays denervation and improves motor function in ALS mice." in: Cell reports, Vol. 2, Issue 3, pp. 497-502, 2012 (PubMed). Wenker, Chamorro, Vota, Callero, Vittori, Nesse: "Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells." in: Journal of cellular biochemistry, Vol. 110, Issue 1, pp. 151-61, 2010 (PubMed).