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  • 产品名称:anti-Discs,LargeHomolog4(Drosophila)(DLG4)(AA18-32)antibody

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  • 产品厂商:SYSY
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简单介绍:
anti-Discs,LargeHomolog4(Drosophila)(DLG4)(AA18-32)antibody
详情介绍:
Immunogen Synthetic peptide DTPPLEHSPAHLPNQ (aa 18-32 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.
Specificity Specific for PSD 95.
Purification antiserum
Alternative Name PSD 95 (DLG4 Antibody Abstract)
Background Synonyms: SAP 90, DLG 4
Pathways Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
Application Notes WB: 1 : 1000 (AP staining)
Restrictions For Research Use only
Format Liquid
Buffer PBS
Handling Advice Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.
Storage 4 °C/-20 °C
Storage Comment Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
Supplier Images
Western Blotting (WB) image for anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (AA 18-32) antibody (ABIN1742271) dilution: 1 : 1000, sample: crude synaptosomal fraction of rat brain (P2)
Product cited in: Bitencourt, Alpár, Cinquina, Ferreira, Pinheiro, Lemos, Ledent, Takahashi, Sialana, Lubec, Cunha, Harkany, Köfalvi: "Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents." in: Neurochemistry international, Vol. 90, pp. 72-84, 2015 (PubMed).

Dervola, Johansen, Walaas, Fonnum: "Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain." in: Neurotoxicology, Vol. 50, pp. 38-45, 2015 (PubMed).

Li, Hu, Höfer, Wong, Cooper, Birnbaum, Hammer, Hofmann: "DHHC5 interacts with PDZ domain 3 of post-synaptic density-95 (PSD-95) protein and plays a role in learning and memory." in: The Journal of biological chemistry, Vol. 285, Issue 17, pp. 13022-31, 2010 (PubMed).

Smalla, Sahin, Putzke, Tischmeyer, Gundelfinger, Kreutz: "Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis." in: Neurochemical research, Vol. 34, Issue 8, pp. 1405-9, 2009 (PubMed).

Norris, Strickland: "Modulation of NR2B-regulated contextual fear in the hippocampus by the tissue plasminogen activator system." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 33, pp. 13473-8, 2007 (PubMed).

Van Damme, Bogaert, Dewil, Hersmus, Kiraly, Scheveneels, Bockx, Braeken, Verpoorten, Verhoeven, Timmerman, Herijgers, Callewaert, Carmeliet, Van Den Bosch, Robberecht: "Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 37, pp. 14825-30, 2007 (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, 2006 (PubMed).

Wong, Schlichter: "Differential recruitment of Kv1.4 and Kv4.2 to lipid rafts by PSD-95." in: The Journal of biological chemistry, Vol. 279, Issue 1, pp. 444-52, 2003 (PubMed).

Von Kriegstein, Schmitz, Link, Südhof: "Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses." in: The European journal of neuroscience, Vol. 11, Issue 4, pp. 1335-48, 1999 (PubMed).