anti-APPantibody(Amyloidbeta(A4)PrecursorProtein)(C-Term) 抗体网

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产品名称：anti-APPantibody(Amyloidbeta(A4)PrecursorProtein)(C-Term)
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产品厂商：SYSY
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简单介绍：

anti-APPantibody(Amyloidbeta(A4)PrecursorProtein)(C-Term)

详情介绍：

Product Details anti-APP Antibody
Product Details anti-APP Antibody
Immunogen	Synthetic peptide GYENPTYKFFEQMQN corresponding to the C-terminus of APP coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.
Specificity	Specific for APP.
Purification	antiserum

Target Details APP
Target Details APP
Alternative Name	APP (APP Antibody Abstract)
Research Area	Signaling
Pathways	Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour

Application Details
Application Details
Application Notes	WB: 1 : 500 up to 1 : 1000 (AP staining) IP: not tested yet ICC: 1 : 500 IHC: not recommended IHC-P: not recommended
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Buffer	PBS
Handling Advice	Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4?°C. Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20?°C),however, is preferable.
Storage	4 °C/-20 °C
Storage Comment	Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

Images
Images
Supplier Images	Indirect immunostaining of PFA fixed mouse hippocampus neurons with anti-APP (dilutio... Immunostaining of a PFA fixed formic acid treated brain section from an triple transg... Images for product: anti-Amyloid beta (A4) Precursor Protein (APP) (C-Term) antibody Indirect immunostaining of PFA fixed mouse hippocampus neurons with anti-APP (dilution 1 : 500; red) and mouse anti-Synapsin 1 (cat. no. 106 011, dilution 1 : 500; green) Immunostaining of a PFA fixed formic acid treated brain section from an triple transgenic Alzheimer mouse with anti-APP (dilution 1 : 200; red) and biotinylated mouse anti-Abeta (cat. no: 218 211BT, dilution 1 : 200, green). Nuclei nuclei have been visualized by DAPI staining (blue).

References for anti-APP antibody (ABIN1742280)
References for anti-APP antibody (ABIN1742280)
Product cited in:	Kumar, Wirths, Theil, Gerth, Bayer, Walter: "Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer's disease." in: Acta neuropathologica, Vol. 125, Issue 5, pp. 699-709, 2013 (PubMed).