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  • 产品名称：anti-SNAP-AssociatedProtein(SNAPIN)(AA117-136),(C-Term)antibody

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  • 产品厂商：SYSY
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简单介绍：
anti-SNAP-AssociatedProtein(SNAPIN)(AA117-136),(C-Term)antibody
详情介绍：
Immunogen Synthetic peptide TARRRAMLDSGVYPPGSPSK (aa 117-136 in rat) coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.
Specificity Specific for snapin.
Purification antiserum
Alternative Name Snapin (SNAPIN Antibody Abstract)
Background Synonyms: Snapap
Pathways Synaptic Membrane, Synaptic Vesicle Exocytosis
Application Notes WB: 1 : 100 - 1 : 5000 (AP staining)
IP: not recommended
ICC: not tested yet
IHC: not recommended
Comment

Since snapin is present in very low concentrations long exposure time is recommended.
Restrictions For Research Use only
Format Liquid
Buffer PBS
Handling Advice Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4?°C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20?°C),however, is preferable.
Storage 4 °C/-20 °C
Storage Comment Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.
Supplier Images
Western Blotting (WB) image for anti-SNAP-Associated Protein (SNAPIN) (AA 117-136), (C-Term) antibody (ABIN1742322) dilution: 1 : 2000
Product cited in: Zhou, Cai, Xie, Sheng: "Snapin recruits dynein to BDNF-TrkB signaling endosomes for retrograde axonal transport and is essential for dendrite growth of cortical neurons." in: Cell reports, Vol. 2, Issue 1, pp. 42-51, 2012 (PubMed).

Zhang, Wada, Yasuhara, Iseda, Eguchi, Fukui, Yang, Yamagata, Hiesberger, Igarashi, Zhang, Wang, Akagi, Kanwar, Makino: "The role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells." in: PLoS ONE, Vol. 2, Issue 5, pp. e414, 2007 (PubMed).

Takamori, Holt, Stenius, Lemke, Gr?nborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gr?ter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, 2006 (PubMed).

Vites, Rhee, Schwarz, Rosenmund, Jahn: "Reinvestigation of the role of snapin in neurotransmitter release." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26251-6, 2004 (PubMed).