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  • 产品名称：anti-Neuroligin1antibody(NLGN1)(AA46-165)

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简单介绍：
anti-Neuroligin1antibody(NLGN1)(AA46-165)
详情介绍：
Immunogen Recombinant protein of rat neuroligin 1 containing the extracellular sequence (aa 46-165).
Specificity Specific for neuroligin 1
Cross-Reactivity (Details) no cross reactivity to neuroligins 2, 3, 4.
Purification Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.
Alternative Name Neuroligin 1 (NLGN1 Antibody Abstract)
Research Area Neurology
Pathways Synaptic Membrane, Synaptic Vesicle Exocytosis
Application Notes WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: not recommended
IHC: not recommended
Restrictions For Research Use only
Format Lyophilized
Reconstitution For reconstitution add 50 μL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
Buffer PBS
Handling Advice Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4?°C for prolonged periods (i.e. several weeks), is not recommended.
Storage -20 °C
Storage Comment Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!
Supplier Images
Western Blotting (WB) image for anti-Neuroligin 1 (NLGN1) (AA 46-165), (Extracellular Domain) antibody (ABIN1742286) dilution: 1 : 1000, sample: crude synaptosomal fraction of rat brain (P2)
Product cited in: Dahlhaus, Hines, Eadie, Kannangara, Hines, Brown, Christie, El-Husseini: "Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus." in: Hippocampus, Vol. 20, Issue 2, pp. 305-22, 2010 (PubMed).