anti-Amyloidbeta40(Abeta40)(AA33-40)antibody 抗体网

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产品名称：anti-Amyloidbeta40(Abeta40)(AA33-40)antibody
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产品厂商：SYSY
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简单介绍：

anti-Amyloidbeta40(Abeta40)(AA33-40)antibody

详情介绍：

Product details
Product details
Immunogen	Synthetic peptide corresponding to aa 33-40 of Abeta 40 coupled to key-hole limpet hemocyanin via an added N-terminal cysteine residue.
Specificity	Specific for Abeta 40
Cross-Reactivity (Details)	no cross reactivity to Abeta 38 and 42.
Purification	Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Target details
Target details
Alternative Name	Abeta 40 (Abeta 40 Antibody Abstract)
Background	Synonyms: Beta-App, ABPP

Application Details
Application Details
Application Notes	WB: 1 : 1000 IP: not tested yet ICC: not tested yet IHC: 1 : 200 up to 1 : 500 IHC-P: 1 : 100 up to 1 : 500
Comment	WB: Detects purified Abeta 40. Complex samples like brain extracts still have to be tested. ELISA: suitable as capture and detector antibody for sandwich-ELISA (protocol for sandwich-ELISA).
Restrictions	For Research Use only

Handling
Handling
Format	Lyophilized
Reconstitution	For reconstitution add 50 μL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.
Buffer	PBS
Handling Advice	Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4?°C for prolonged periods (i.e. several weeks), is not recommended.
Storage	-20 °C
Storage Comment	Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

Images
Images
Supplier Images	Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 100... anti-Amyloid beta 40 (Abeta 40) (AA 33-40) antibody (Image 2) Indirect immunostaining of a PFA fixed brain section from a 5XFAD mouse (dilution 1 :... Immunostaining of paraffin embedded brain section from an Alzheimer's patient (diluti... Images for product: anti-Amyloid beta 40 (Abeta 40) (AA 33-40) antibody Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 1000) and a commercially available monoclonal anti-Abeta antibody. anti-Amyloid beta 40 (Abeta 40) (AA 33-40) antibody (Image 2) Indirect immunostaining of a PFA fixed brain section from a 5XFAD mouse (dilution 1 : 500; green). Immunoreactivity in amyloid plaques was revealed using fluorochromated secondary antibodies. Nuclei have been visualized by DAPI staining. Immunostaining of paraffin embedded brain section from an Alzheimer's patient (dilution 1 : 100). Immunoreactivity in amyloid plaques was revealed using diaminobenzidine as chromagen. Nuclei were counterstained with haematoxylin (blue).

References
References
Product cited in:	Christensen, Huettenrauch, Mitkovski, Pradier, Wirths: "Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal A? accumulation." in: Frontiers in aging neuroscience, Vol. 6, pp. 139, 2014 (PubMed).