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Characteristics
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PubChem CID: N/A
Molecular Formula: C₂₄H₂₈ClN₅O
Cell Premeable: Yes Salt form: No GSK-106 is a useful negative control for PAD4 inhibitors (GSK-121 and GSK-484). It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils (IC₅₀s > 100 μM). Smiles: O=C(N1CC(N)CCC1)C2=CC=C3C(N(C)C(C(N4CC)=CC5=C4C=CC=C5)=N3)=C2.[H]Cl InChi: InChI=1S/C24H27N5O.ClH/c1-3-29-20-9-5-4-7-16(20)13-22(29)23-26-19-11-10-17(14-21(19)27(23)2)24(30)28-12-6-8-18(25)15-28,/h4-5,7,9-11,13-14,18H,3,6,8,12,15,25H2,1-2H3,1H Inchi Key: VRPFLFUQMWOJAT-UHFFFAOYSA-N
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