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  • 产品名称：AZD-3759

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  • 产品厂商：Biovision
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AZD-3759
详情介绍：
Purpose A potent epidermal growth factor receptor (EGFR) inhibitor
Characteristics AZD-3759 is a potent epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. AZD-3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. This prevents EGFR-mediated signaling, and may lead to both induction of cell death and inhibition of tumor growth in EGFR-overexpressing cells.
Purity ≥ 98 % by HPLC
Chemical Name (R)-4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl 2,4-dimethylpiperazine-1-carboxylate
Formula C₂₂H₂₃ClFN₅O₃
Permeability Cell-permeable
Molecular Weight 459.9 g/mol
CAS-No 1626387-80-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months