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PubChem CID: 16255105
Molecular Formula: C₁₆H₁₈N₂.HCl
Cell Premeable: Yes Salt form: No PhiKan083 is a p53 stabilizing agent
preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan083 slows rate of thermal denaturation of p53-Y220C. Smiles: CCN1C2=C(C=C(C=C2)CNC)C3=CC=CC=C31.Cl InChi: InChI=1S/C16H18N2.ClH/c1-3-18-15-7-5-4-6-13(15)14-10-12(11-17-2)8-9-16(14)18
/h4-10,17H,3,11H2,1-2H3
1H Inchi Key: IXWVUPURFWFRNE-UHFFFAOYSA-N
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