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  • 产品名称:Dapagliflozin

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  • 产品厂商:Biovision
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简单介绍:
Dapagliflozin
详情介绍:
Characteristics

PubChem CID: 9887712
Molecular Formula: C₂₁H₂₅ClO₆
Cell Premeable: Yes

Dapagliflozin is a selective SGLT (sodium-glucose cotransporter) inhibitor that blocks glucose transport with about 100-fold selectivity for SGLT2 (Ki = 6 nM
EC₅₀ = 1.1 nM) over SGLT1 (Ki = 390 nM). An antidiabetic agent.

Smiles: CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)CO)O)O)O)Cl

InChi: InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1

Inchi Key: JVHXJTBJCFBINQ-ADAARDCZSA-N

Purity ≥ 98 % by HPLC
Chemical Name (1S)-​1,​5-​anhydro-​1-​C-​[4-​chloro-​3-​[(4-​ethoxyphenyl)methyl]phenyl]-​D-​glucitol
Formula C₂₁H₂₅ClO₆
Permeability Cell-permeable
Background Synonyms: (1S)-​1,​5-​anhydro-​1-​C-​[4-​chloro-​3-​[(4-​ethoxyphenyl)methyl]phenyl]-​D-​glucitol
Molecular Weight 408.87 g/mol
CAS-No 461432-26-8
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months