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  • 产品名称：GSK461364

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  • 产品厂商：Biovision
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简单介绍：
GSK461364
详情介绍：
Characteristics A potent, selective and ATP-competitive inhibitor of Polo Like Kinase 1 (PLK1) (Ki = 2 nM). Displays > 100-fold selectivity for PLK1 over PLK2 and PLK3. Shows anti-proliferative activity against several tumor cell lines.
Purity ≥ 98 % by HPLC
Chemical Name 5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-((R)-1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide
Formula C₂₇H₂₈F₃N₅O₂S
Permeability Cell-permeable
Molecular Weight 543.60 g/mol
CAS-No 929095-18-1
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 36 months
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