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  • 产品名称：GSK-690693

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  • 产品厂商：Biovision
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简单介绍：
GSK-690693
详情介绍：
Characteristics An ATP-competitive pan-Akt kinase inhibitor. Inhibits Akt kinase isoforms 1, 2, 3 with IC50values of 2, 13, and 9 nM, respectively. Inhibited proliferation and induced apoptosis in a subset of tumor cells with potency consistent with intracellular inhibition of Akt kinase activity.
Purity ≥ 98 % by HPLC
Chemical Name 4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)--1-ethyl-7-[(3S)-3-piperidinylmethoxy)-1H-imidazo[-4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol
Formula C₂₁H₂₇N₇O₃
Permeability Cell-permeable
Molecular Weight 425.48 g/mol
CAS-No 937174-76-0
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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