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  • 产品名称：AT-101

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  • 产品厂商：Biovision
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简单介绍：
AT-101
详情介绍：
Characteristics AT-101 is the R-(-) enantiomer of Gossypol that acts as an inhibitor of the antiapoptotic Bcl proteins (Bcl-2, Bcl-XL, Bcl-W, and Mcl-1) and an inducer of the pro-apoptotic proteins noxa and puma. It induces apoptosis in drug-resistant multiple myeloma cell lines. Apoptosis is activated by the mitochondrial pathway.
Purity ≥ 98 % by TLC
Chemical Name (-)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dim-ethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8-,8'-dicarboxaldehyde; (R)-Gossypol
Formula C₃₀H₃₀O₈
Permeability Cell-permeable
Molecular Weight 518.56 g/mol
CAS-No 90141-22-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for AT-101 (ABIN1685777) AT-101