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Characteristics
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A cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin). Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be preferred for short-term studies. Acts via a different mechanism than cytochalasins.
Synonyms: LAT-B, NSC 339663
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