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Characteristics
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A relatively non-toxic Inhibitor of histone deacetylase (HDAC). Facilitates transcriptional activation (TGF-beta/Smad4) in both stable and transient receptor assays in a concentration-dependent manner. At approx. 2 µg/mL (6-8 µM) concentrations, results in a greater than 100-fold increase in histone acetylation in PANC-1 cells.
Synonyms: N-Hydroxy-1,3-dioxo-1H-benz[de]isoquinoline-2(3H)-hexanamide
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