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  • 产品名称：Doramapimod

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  • 产品厂商：Biovision
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简单介绍：
Doramapimod
详情介绍：
Characteristics Cell-permeable. A potent protein kinase inhibitor with a >330-fold selectivity for p38 MAPK compared with 12 other protein kinases. In contrast to other p38 MAPK inhibitors (e.g., SB203580), doramapimod prevents both the kinetic activity and phosphorylation of p38 MAPK by binding to the ATP pocket as well as to a novel allosteric on p38 MAPK.
Purity ≥ 98 % by HPLC
Chemical Name 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea; BRRB 796
Formula C₃₁H₃₇N₅O₃
Permeability Cell-permeable
Molecular Weight 527.66 g/mol
CAS-No 285983-48-4
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 48 months
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