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  • 产品名称：PI-103

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  • 产品厂商：Biovision
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简单介绍：
PI-103
详情介绍：
Characteristics A cell-permeable, ATP-competitive inhibitor of phosphatidylinositol 3-kinase (PI3K) family members with selectivity toward DNA-PK, PI3K (p110alpha), and mTOR. The IC50 values are 2, 8, 20, 26, 48, 83, 88, 150 nM for DNA-PK, p110alpha, mTORC1, PI3-KC2beta, p110delta, mTORC2, p110beta, and p110gamma, respectively. Inhibits growth of human tumor xenografts in mice in vivo.
Purity ≥ 98 % by HPLC
Chemical Name 3-(4-(4-Morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl)phenol
Formula C₁₉H₁₆N₄O₃
Permeability Cell-permeable
Molecular Weight 348.36 g/mol
CAS-No 371935-74-9
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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image for PI-103 (ABIN412328) PI-103