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  • 产品名称：NVP-BHG712

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  • 产品厂商：Biovision
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简单介绍：
NVP-BHG712
详情介绍：
Purpose A potent, selective small-molecule inhibitor of the receptor tyrosine kinase EphB4
Characteristics Off-white solid
Molecular formular: C26H20F3N7O
Purity ≥ 98 % by HPLC
Chemical Name 4-Methyl-3-[[1-methyl-6-(3-pyridiny l)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(t rifluoromethyl)phenyl]benzamide
Formula C₂₆H₂₀F₃N₇O
Permeability Cell-permeable
Molecular Weight 503.48 g/mol
CAS-No 940310-85-0
Comment

Synonyms:
4-Methyl-3-[[1-methyl-6-(3-pyridiny l)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(t rifluoromethyl)phenyl]benzamide
A potent, selective small-molecule inhibitor of the receptor tyrosine kinase EphB4 (ED = 25 nM). Displays selectivity for EphB4 over >40 other kinases in vitro, including FGFR3. NVP-BHG712 blocks Ephrin receptor autophosphorylation and VEGF-induced angiogenesis
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
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