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  • 产品名称：BMS-777607

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  • 产品厂商：Biovision
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简单介绍：
BMS-777607
详情介绍：
Purpose A potent, selective and ATP-competitive Met kinase superfamily inhibitor
Characteristics White to off-white solid
Molecular formular: C25H19ClF2N4O4
Purity ≥ 98 % by HPLC
Chemical Name N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
Formula C₂₅H₁₉ClF₂N₄O₄
Permeability Cell-permeable
Molecular Weight 512.89 g/mol
CAS-No 1025720-94-8
Comment

Synonyms:
N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
A potent, selective and ATP-competitive Met kinase superfamily inhibitor (IC = 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM for c-Met, Axl, RON, and Tyro-3, respectively). it was >40-fold selective for Met kinase family targets versus Lck, VEGFR-2, and TrkA/B and > 500-fold selective versus all other receptor and non-receptor kinases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
image for BMS-777607 (ABIN1889126) BMS-777607