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  • 产品名称:ML243

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  • 产品厂商:Biovision
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简单介绍:
ML243
详情介绍:
Purpose ML-243 is a selective inhibitor of cancer stem cells
Characteristics White solid
Molecular formular: C14H16N2OS
Purity ≥ 98 % by HPLC
Chemical Name (2E)​-​N-​​(4,​​5-​​dihydro-​​2-​​thiazolyl)​-​​3-​​(4-​​ethylphenyl)​-​2-​​propenamide; CID-50910523
Formula C₁₄H₁₆N₂OS
Permeability Cell-permeable
Molecular Weight 260.35 g/mol
CAS-No 1426576-80-8
Comment

Synonyms:
(2E)-N-(4,5-dihydro-2-thiazolyl)-3-(4-ethylphenyl)-2-propenamide, CID-50910523
ML-243 is a selective inhibitor of cancer stem cells. Displays 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC = 2.0 µM) over a control (mammary epithelial) cell line (EC = 64 µM). It weakly antagonizes the adenosine A2A receptor (IC = 10 µM) and has no effect on 68 other targets commonly used in drug discovery for lead profiling

Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 24 months
Supplier Images
 image for ML243 (ABIN1889040) ML243