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  • 产品名称：AktInhibitor,Isozyme-Selective

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  • 产品厂商：Biovision
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简单介绍：
AktInhibitor,Isozyme-Selective
详情介绍：
Purpose An Akt inhibitor (Isozyme-Selective)
Characteristics A potent and selective inhibitor of Akt1/Akt2 activity (IC50 = 58 nM (Akt1), 210 nM (Akt2) and 2.12 µM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50 µM).
Purity ≥ 97 % by HPLC
Chemical Name 1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one; Akti-1/2
Formula C₃₄H₂₉N₇O
Permeability Cell-permeable
Solubility DMSO
Molecular Weight 551.65 g/mol
CAS-No 612847-09-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 24 months
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