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  • 产品名称：GSK-3Inhibitor,AR-A014418

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  • 产品厂商：Biovision
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GSK-3Inhibitor,AR-A014418
详情介绍：
Purpose A selective GSK-3 inhibitor
Characteristics A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Inhibition is competitive with respect to ATP (Ki = 38nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 µM) and over 26 other kinases. Inhibits beta-amyloid-mediated neurodegeneration in hippocampal slices.
Purity ≥ 98 % by TLC
Chemical Name N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea
Formula C₁₂H₁₂N₄O₄S
Permeability Cell-permeable
Solubility DMSO (30 mg/mL)
Molecular Weight 308.31 g/mol
CAS-No 487021-52-3
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and air
Storage -20 °C
Expiry Date 48 months
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