产品详情
所在位置: 首页> 产品目录> 辅助试剂>
查看大图

  • 产品名称：EZSolution™GDC-0449

  • 产品型号：
  • 产品厂商：Biovision
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
EZSolution™GDC-0449
详情介绍：
Purpose A potent inhibitor of Smoothened (SMO)
Brand EZSolution™
Characteristics Molecular formular: C19H14Cl2N2O3S
Purity ≥ 98 % by HPLC
Chemical Name 2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide; HhAntag691
Formula C₁₉H₁₄Cl₂N₂O₃S
Permeability Cell-permeable
Molecular Weight 421.3 g/mol
CAS-No 879085-55-9
Comment

Synonyms:
2-Chloro-N-(4-chloro-3-(pyridine-2-yl)phenyl)-4-(methylsulfonyl)benzamide, HhAntag691
A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth
Restrictions For Research Use only
Format Liquid
Concentration 10 mM
Buffer anhydrous DMSO
Handling Advice Protect from air and moisture
Storage -20 °C
Expiry Date 12 months
Supplier Images
image for EZSolution™ GDC-0449 (ABIN1888967) EZSolution™ GDC-0449