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  • 产品名称：Dynasore

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  • 产品厂商：Biovision
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简单介绍：
Dynasore
详情介绍：
Characteristics Cell-permeable. A reversible, noncompetitive inhibitor of dynamin that interferes in vitro with the GTPase activity of dynamin1, dynamin2, and Drp1, the mitochondrial dynamin, but not of other small GTPases. Dynasore acts as a potent inhibitor of endocytic pathways known to depend on dynamin by rapidly blocking coated vesicle formation within seconds of dynasore addition.
Purity ≥ 98 % by NMR
Chemical Name 3-Hydroxy-naphthalene-2-carboxylic acid (3,4-dihydroxy-benzylidene)-hydrazide
Formula C₁₈H₁₄N₂O₄ . H₂O
Permeability Cell-permeable
Molecular Weight 322.31 .18.0 g/mol
CAS-No 304448-55-3
Research Area Kinases/Phosphatases
Restrictions For Research Use only
Format Solid
Handling Advice Protect from air and light
Storage -20 °C
Expiry Date 36 months
Supplier Images
image for Dynasore (ABIN629279) Dynasore
Product cited in: Bourassa, Tudashki, Pineyro, Grandbois, Gendron: "Label-free monitoring of μ-opioid receptor-mediated signaling." in: Molecular pharmacology, Vol. 86, Issue 2, pp. 138-49, 2014 (PubMed).