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  • 产品名称：Saracatinib(AZD0530)

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  • 产品厂商：Biovision
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简单介绍：
Saracatinib(AZD0530)
详情介绍：
Characteristics AZD0530 is a dually active inhibitor of c-Src and Bcr-ABL, on bone resorption. AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of focal adhesion kinase (FAK) and paxillin in a dose-dependent manner in a Calu-6 Xenograft model.
Purity ≥ 99 % by HPLC
Chemical Name AZD-0530
Formula C₂₇H₃₂ClN₅O₅
Permeability Cell-permeable
Molecular Weight 542.03 g/mol
CAS-No 379231-04-6
Restrictions For Research Use only
Format Solid
Handling Advice Protect from light and moisture
Storage -20 °C
Expiry Date 24 months
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image for Saracatinib (AZD0530) (ABIN412161) Saracatinib (AZD0530)
Product cited in: Kanou, Oneyama, Kawahara, Okimura, Ohta, Ikeda, Shintani, Okumura, Okada: "The transmembrane adaptor Cbp/PAG1 controls the malignant potential of human non-small cell lung cancers that have c-src upregulation." in: Molecular cancer research : MCR, Vol. 9, Issue 1, pp. 103-14, 2011 (PubMed).