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  • 产品名称：BakBH3Peptide

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  • 产品厂商：BioLeaf
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简单介绍：
BakBH3Peptide
详情介绍：
Sequence One-letter code: GQVGRQLAII GDDIN, Three-letter code: {Gly}{Gln}{Val}{Gly}{Arg}{Gln}{Leu}{Ala}{Ile}{Ile}{Gly}{Asp}{Asp}{Ile}{Asn}{Arg
Characteristics Formula: C72H125N25O24
Purity > 95 %
Background This peptide, generated from the BH3 domain of Bak (Flu-BakBH3), has been shown to have high-affinity binding to a surface pocket of the Bcl-XL protein that is required for its death antagonist function. Synonym: Bak BH3
Molecular Weight 1724.9
Restrictions For Research Use only
Format Lyophilized
Storage -20 °C
Product cited in: Ku, Liang, Jung, Oh: "Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX." in: Cell research, Vol. 21, Issue 4, pp. 627-41, 2011 (PubMed).