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Background
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This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. The protein localizes to the endoplasmic reticulum and mitochondria-associated membranes. The gene is within the Smith-Magenis syndrome region on chromosome 17. Alternate splicing of this gene results in three transcript variants encoding two different isoforms.
Alias Symbols: PNMT, PEAMT, PEMPT, PEMT2, MGC2483
Protein Interaction Partner: SPP1,
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