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  • 产品名称：Ratanti-Mouse(Murine)IgD(HeavyChain)Antibody

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  • 产品厂商：BioLeaf
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简单介绍：
Ratanti-Mouse(Murine)IgD(HeavyChain)Antibody
详情介绍：
Clone 11-26c
Isotype IgG2a
Characteristics The antibody detects: heavy chain of mouse IgD
The monoclonal antibody 11-26 reacts with mouse IgD of all haplotypes (e.g., IgDa, IgDb, IgDc), and does not react with other immunoglobulin isotypes.1 11-26 does not induce proliferation of mature B cells in vitro,5 nor does in vivo injection of the monoclonal antibody have any effect on activation of mature B lymphocytes.
Purification Purified
Research Area Stem Cells, Hematopoietic Progenitors, Secondary Antibodies
Application Notes Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Buffer 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
Preservative Without preservative
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Product cited in: Mielke, Schwarzer, Calkhoven, Kaufman, D?rken, Leutz, Jundt: "Eukaryotic initiation factor 2alpha phosphorylation is required for B-cell maturation and function in mice." in: Haematologica, Vol. 96, Issue 9, pp. 1261-8, 2011 (PubMed).

Background publications Nitschke, Kosco, K?hler, Lamers: "Immunoglobulin D-deficient mice can mount normal immune responses to thymus-independent and -dependent antigens." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 5, pp. 1887-91, 1993 (PubMed).