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  • 产品名称：TransientReceptorPotentialCationChannel,SubfamilyC,Member3(TRPC3)Peptide

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  • 产品厂商：PromoCell
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简单介绍：
TransientReceptorPotentialCationChannel,SubfamilyC,Member3(TRPC3)Peptide
详情介绍：
Blocked Antibody anti-TRPC3 antibody (Transient Receptor Potential Cation Channel, Subfamily C, Member 3) (C-Term) (ABIN1003365)
Characteristics 14 amino acids near the carboxy terminus of human TRPC3.
Research Area Cardiovascular, Hypertrophy, Ion Channels
Application Notes TRPC3 peptide is used for blocking the activity of TRPC3 antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37˚C.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Background publications Chariot, Leonardi, Muller, Bonif, Brown, Siebenlist: "Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases." in: The Journal of biological chemistry, Vol. 277, Issue 40, pp. 37029-36, 2002 (PubMed).

Pomerantz, Baltimore: "NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase." in: The EMBO journal, Vol. 18, Issue 23, pp. 6694-704, 2000 (PubMed).

Cheng, Baltimore: "TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation." in: Genes & development, Vol. 10, Issue 8, pp. 963-73, 1996 (PubMed).

Rothe, Xiong, Shu, Williamson, Goddard, Goeddel: "I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8241-6, 1996 (PubMed).