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  • 产品名称：Toll-Interleukin1Receptor(TIR)DomainContainingAdaptorProtein(TIRAP)(C-Term)Pept

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  • 产品厂商：PromoCell
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简单介绍：
Toll-Interleukin1Receptor(TIR)DomainContainingAdaptorProtein(TIRAP)(C-Term)Peptide
详情介绍：
Blocked Antibody anti-TIRAP antibody (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein) (C-Term) (ABIN1003284)
Characteristics 15 amino acids near the carboxy terminus of mouse TIRAP.
Application Notes TIRAP peptide is used for blocking the activity of TIRAP antibody . It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37ºC.
Restrictions For Research Use only
Format Liquid
Concentration 200 µg/mL
Buffer Supplied in PBS pH 7.2 (10 mM NaH₂PO₄, 10 mM Na₂HPO₄, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice For products with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap. The peptide solution should be gently mixed before use.
Storage -20 °C
Storage Comment Store at -20°C, stable for one year.
Expiry Date 12 months
Product cited in: Cascalho: "Advantages and disadvantages of cytidine deamination." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 11, pp. 6513-8, 2004 (PubMed).

Greeve, Philipsen, Krause, Klapper, Heidorn, Castle, Janda, Marcu, Parwaresch: "Expression of activation-induced cytidine deaminase in human B-cell non-Hodgkin lymphomas." in: Blood, Vol. 101, Issue 9, pp. 3574-80, 2003 (PubMed).

Background publications Muramatsu, Kinoshita, Fagarasan, Yamada, Shinkai, Honjo: "Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme." in: Cell, Vol. 102, Issue 5, pp. 553-63, 2000 (PubMed).

Muramatsu, Sankaranand, Anant, Sugai, Kinoshita, Davidson, Honjo: "Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells." in: The Journal of biological chemistry, Vol. 274, Issue 26, pp. 18470-6, 1999 (PubMed).