产品详情
所在位置: 首页> 产品目录> 二抗>
查看大图

  • 产品名称：Mouseanti-HumanIg(Chainkappa),(LightChain)Antibody

  • 产品型号：
  • 产品厂商：BioLeaf
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Mouseanti-HumanIg(Chainkappa),(LightChain)Antibody
详情介绍：
Clone A8B5
Isotype IgG1
Specificity The antibody A8B5 reacts with kappa light chains (22.5 kDa) of immunoglobulins.
No Cross-Reactivity Hamster, Sheep (Ovine), Goat, Rabbit, Guinea Pig
Purification Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Background Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda, both having a molecular weight of 22.5 kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Supplier Images
Flow Cytometry (FACS) image for Mouse anti-Human Ig (Chain kappa), (Light Chain) Antibody (ABIN457414) B lymphocytes (CD19 +) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain dete...
Product cited in: Scheeren, Diehl, Smit, Beaumont, Naspetti, Bende, Blom, Karube, Ohshima, van Noesel, Spits: "IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis." in: Blood, Vol. 111, Issue 9, pp. 4706-15, 2008 (PubMed).

Konig, Wennemuth, Soyer, Hoffmann, Happle, Krause: "Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma." in: European journal of dermatology : EJD, Vol. 9, Issue 1, pp. 29-31, 1999 (PubMed).

Background publications Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).