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  • 产品名称：ProteintyrosinePhosphatase,ReceptorType,D(PTPRD)(AA21-1265)(Active)protein(Hist

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  • 产品厂商：ACROBiosystems
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简单介绍：
ProteintyrosinePhosphatase,ReceptorType,D(PTPRD)(AA21-1265)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 140 kDa. The protein migrates as 19 kDa and 120-130 kDa under reducing (R) condition (SDS-PAGE).
Purity >90 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Receptor-type tyrosine-protein phosphatase delta is an enzyme that is encoded by the PTPRD gene. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRD has been shown to interact with PTPRS and liprin-alpha-1. Studies of the similar genes in chick and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple tissue specific alternatively spliced transcript variants of this gene have been reported. Mutations in the PTPRD gene are associated with autism, obsessive-compulsive disorder, and breast cancer.
Molecular Weight 140 kDa
NCBI Accession NP_002830
Pathways Synaptic Membrane
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Storage -20 °C