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  • 产品名称：TransferrinReceptor2(TFR2)(AA103-798)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
TransferrinReceptor2(TFR2)(AA103-798)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a mouse IgG1 Fc tag at the N-terminus, and has a calculated MW of 103.2 kDa. The predicted N-terminus is Ile. The reducing (R) protein migrates as 116 kDa in SDS-PAGE due to glycosylation.
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
Molecular Weight 103.2 kDa
UniProt Q9JKX3
Pathways Transition Metal Ion Homeostasis
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Transferrin Receptor 2 (TFR2) (AA 103-798) (Active) protein (Fc Tag) (ABIN4949192) Mouse Transferrin R2, mouse IgG1 Fc Tag on SDS-PAGE under reducing (R) condition. The...