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  • 产品名称：TumorNecrosisFactor(Ligand)Superfamily,Member18(TNFSF18)(AA47-173)(Active)prote

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  • 产品厂商：ACROBiosystems
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简单介绍：
TumorNecrosisFactor(Ligand)Superfamily,Member18(TNFSF18)(AA47-173)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 41.4 kDa. As a result of glycosylation, the protein migrates as 45 kDa under reducing (R) condition, and 80-100 kDa under non-reducing (NR) condition (SDS-PAGE).
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
Molecular Weight 41.4 kDa
Research Area Growth Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Storage -20 °C
Supplier Images
Binding Studies (Bind) image for Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 47-173) (Active) protein (Fc Tag) (ABIN4949171) Immobilized Mouse GITR, His Tag with a linear range of 0.007-0.256 μg/mL.
SDS-PAGE (SDS) image for Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (AA 47-173) (Active) protein (Fc Tag) (ABIN4949171) Mouse GITR Ligand / TNFSF18, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (N...