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  • 产品名称：Butyrophilin,Subfamily3,MemberA1(BTN3A1)(AA30-254)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Butyrophilin,Subfamily3,MemberA1(BTN3A1)(AA30-254)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.8 kDa. As a result of glycosylation, the protein migrates as 55 kDa under reducing (R) condition, and 100-120 kDa under non-reducing (NR) condition (SDS-PAGE).
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
Molecular Weight 50.8 kDa
UniProt O00481
Pathways Activated T Cell Proliferation
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Butyrophilin, Subfamily 3, Member A1 (BTN3A1) (AA 30-254) (Active) protein (Fc Tag) (ABIN4949084) Human BTN3A1, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. ...