产品详情
查看大图

  • 产品名称：Jagged1(JAG1)(Active)protein(Histag)

  • 产品型号：
  • 产品厂商：ACROBiosystems
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Jagged1(JAG1)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 112.3 kDa. The protein migrates as 160-180 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >92 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in ***** and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).
Molecular Weight 112.3 kDa
NCBI Accession NP_000205
UniProt P78504
Pathways Notch Signaling, Stem Cell Maintenance
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -70 °C.
Supplier Images
SDS-PAGE (SDS) image for Jagged 1 (JAG1) (Active) protein (His tag) (ABIN2181410) Human Jagged 1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained...