产品详情
查看大图

  • 产品名称：TransferrinReceptor(p90,CD71)(TFRC)(AA89-760)(Active)protein(Histag)

  • 产品型号：
  • 产品厂商：ACROBiosystems
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
TransferrinReceptor(p90,CD71)(TFRC)(AA89-760)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 76 kDa. The protein migrates as 80-85 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >92 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
ProductDetails: Biological Activity Comment Biological Activity: Measured by its binding ability in a functional ELISA. Immobilized rh CD71 /TFR at 10 μg/mL ( 100 μL/well ) can bind human Transferrin. The EC50 of human Transferrin is 6.4 ng/mL.
Background CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.
Molecular Weight 76 kDa
UniProt P02786
Pathways Transition Metal Ion Homeostasis
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer PBS, pH 7.4
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) (Active) protein (His tag) (ABIN2180829) Human Transferrin R, His Tag on SDS-PAGE under reducing (R) condition. The gel was st...
Binding Studies (Bind) image for Transferrin Receptor (p90, CD71) (TFRC) (AA 89-760) (Active) protein (His tag) (ABIN2180829) Immobilized Human Transferrin, His Tag with a linear range of 0.4-6 ng/mL.