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  • 产品名称：Butyrophilin,Subfamily1,MemberA1(BTN1A1)(AA27-242)(Active)protein(FcTag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
Butyrophilin,Subfamily1,MemberA1(BTN1A1)(AA27-242)(Active)protein(FcTag)
详情介绍：
Characteristics This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE).
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Molecular Weight 50.6 kDa
UniProt Q13410
Research Area Cardiovascular
Pathways Activated T Cell Proliferation
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 100 mM Glycine, pH 7.5
Storage -20 °C
Supplier Images
SDS-PAGE (SDS) image for Butyrophilin, Subfamily 1, Member A1 (BTN1A1) (AA 27-242) (Active) protein (Fc Tag) (ABIN4949082) Human BTN1A1, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. ...