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  • 产品名称：CD47(CD47)(AA19-139)(Active)protein(AVItag,Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
CD47(CD47)(AA19-139)(Active)protein(AVItag,Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 16.9 kDa. The protein migrates as 33-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >95 % as determined by SDS-PAGE.
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal ***** tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
Molecular Weight 16.9 kDa
NCBI Accession NP_942088
UniProt Q08722
Research Area Surface Receptors of Immune Cells, CD Antigens
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 10 mM Bicine, pH 8.3
Storage -20 °C
Supplier Images
Binding Studies (Bind) image for CD47 (CD47) (AA 19-139) (Active) protein (AVI tag,His tag) (ABIN4949217) Immobilized Anti-CD47 MAb, Human IgG4 at 2μg/mL (100 μL/well) can bind Unconjugated H...
Binding Studies (Bind) image for CD47 (CD47) (AA 19-139) (Active) protein (AVI tag,His tag) (ABIN4949217) Immobilized Human SIRP alpha, Fc Tag with a linear range of 2-12.8 ng/mL.
SDS-PAGE (SDS) image for CD47 (CD47) (AA 19-139) (Active) protein (AVI tag,His tag) (ABIN4949217) Unconjugated Human CD47, His Tag & Avi Tag on SDS-PAGE under reducing (R) condition. ...