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  • 产品名称：FetuinB(FETUB)(AA16-382)(Active)protein(Histag)

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  • 产品厂商：ACROBiosystems
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简单介绍：
FetuinB(FETUB)(AA16-382)(Active)protein(Histag)
详情介绍：
Characteristics This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.4 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity >95 % as determined by SDS-PAGE.
Sterility 0.22 μm filtered
Endotoxin Level Less than 1.0 EU per μg by the LAL method.
Background Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.
Molecular Weight 42.4 kDa
Restrictions For Research Use only
Format Lyophilized
Reconstitution Please see Certificate of Analysis for specific instructions. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Buffer 50 mM Tris, 150 mM NaCl, pH 8.0
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
Supplier Images
SDS-PAGE (SDS) image for Fetuin B (FETUB) (AA 16-382) (Active) protein (His tag) (ABIN2181086) Human Fetuin B, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained...
Background publications Dietzel, Kolesnikova, Maisner: "Actin filaments disruption and stabilization affect measles virus maturation by different mechanisms." in: Virology journal, Vol. 10, pp. 249, 2013 (PubMed).

Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: "The DNA sequence, annotation and analysis of human chromosome 3. ..." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, 2006 (PubMed).